To tell friends and family about their naloxone and to keep it in a place where friends and family can entry it within an crisis,
Stay away from using acetaminophen and codeine phosphate tablets in adolescents 12 to eighteen yrs of age who have other hazard elements that may raise their sensitivity to your respiratory depressant results of codeine Except the benefits outweigh the dangers.
-Doses increased than sixty mg haven't been shown to improve discomfort relief and therefore are linked to a heightened incidence of adverse outcomes.
When taking acetaminophen and codeine phosphate tablets: Will not change your dose. Choose acetaminophen and codeine phosphate tablets accurately as prescribed by your Health care supplier. Use the bottom dose attainable for your shortest time required. For acute (shorter-expression) ache, chances are you'll only ought to get acetaminophen and codeine phosphate tablets for a few days.
Though critical, life-threatening, or deadly respiratory depression can happen at any time during the use of acetaminophen and codeine phosphate tablets, the risk is greatest throughout the initiation of therapy or adhering to a dosage improve.
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Talk about the availability of naloxone to the crisis therapy of opioid overdose With all the individual and caregiver and assess the possible have to have for entry to naloxone, the two when initiating and renewing treatment with acetaminophen and codeine phosphate tablets (see WARNINGS, Everyday living-Threatening Respiratory Despair; PRECAUTIONS, Data for Individuals/Caregivers).
Parenteral drug abuse is usually related to transmission of infectious illnesses like hepatitis and HIV.
This isn't a complete list of achievable Unintended effects. If you detect other consequences not mentioned earlier mentioned, Make contact with your health practitioner or pharmacist.
seventy eight periods the MHDD (based on a body surface area comparison) and there was check here a reduction in the number of mating pairs making a fifth litter at this dose, suggesting the probable for cumulative toxicity with Serious administration of acetaminophen near the higher limit of each day dosing.
Usage of cytochrome P450 3A4 inducers, 3A4 inhibitors, or 2D6 inhibitors with acetaminophen and codeine phosphate tablets necessitates thorough thing to consider of the results over the dad or mum drug, codeine, click here plus the Energetic metabolite, morphine.
Do not abruptly discontinue acetaminophen and codeine phosphate tablets in the patient physically depending on get more info opioids. Quick tapering of acetaminophen and codeine phosphate tablets inside of a individual bodily dependent on opioids may more info well produce significant withdrawal signs or symptoms, uncontrolled discomfort, and read more suicide.
•Shop Acetaminophen and Codeine Phosphate Tablets, USP securely, from sight and achieve of youngsters, As well as in a location not accessible by Other individuals, like website visitors to the home.
Opioid Analgesic REMS: To ensure that the advantages of opioid analgesics outweigh the dangers of addiction, abuse, and misuse, a REMS is needed for these merchandise. Beneath the necessities on the REMS, drug corporations with permitted opioid analgesic solutions ought to make REMS-compliant education schemes accessible to Health care vendors.